There are many examples in the literature where a phenyl or alkyl group has been replaced by ferrocene as a drug design strategy. However, the anticipated outcome
(increase in activity) has not always been encountered. In some instances, the introduction of ferrocene abolished or markedly reduced activity in the resulting compound. In other cases, activity was more or less retained. There are also instances where an increase in activity or an unexpected change in activity profile was detected. Some of these examples are discussed in the following paragraphs.
Was this article helpful?
Learning About 10 Ways Fight Off Cancer Can Have Amazing Benefits For Your Life The Best Tips On How To Keep This Killer At Bay Discovering that you or a loved one has cancer can be utterly terrifying. All the same, once you comprehend the causes of cancer and learn how to reverse those causes, you or your loved one may have more than a fighting chance of beating out cancer.