W

OH O

Figure 2.19 Boron-containing nucleotides

Kaczmarczyk on the syntheses of some phosphate esters having attached boron cages, as shown in Figure 2.20.48 Other, neutral, phosphorus-containing car-boranes have also been reported, several of which are shown in Figure 2.21.

Preliminary studies show that many of these compounds are highly toxic. However, more complete biological assessments of boron-containing phosphates and phosphonates, as potential tumor-targeting BNCT agents, remain to be carried out.

Figure 2.20 Phosphate esters of polyhedral boranes

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