1. Wasinger VC, Cordwell SJ, Cerpa-Poljak A et al. Progress with gene-product mapping of the Molli-cutes: Mycoplasma genitalium. Electrophoresis 1995;16:1090-1094.

2. O'Farrell PH. High resolution two-dimensional electrophoresis of proteins.,/ Biol Chem 1975; 250:4007-4021.

3. Simpson RJ, Connolly LM, Eddes JS et al. Proteomic analysis of the human colon carcinoma cell line (LIM 1215): development of a membrane protein database. Electrophoresis 2000;21:1707-1732.

4. Ha GH, Lee SU, Kang DG et al. Proteome analysis of human stomach tissue: separation of soluble proteins by two-dimensional polyacrylamide gel electrophoresis and identification by mass spectrometry. Electrophoresis 2002;23:2513-2524.

5. Steel LF, Mattu TS, Mehta A et al. A proteomic approach for the discovery of early detection markers of hepatocellular carcinoma. Dis Markers 2001;17:179-189.

6. Aebersold R, Mann M. Mass spectrometry-based proteomics. Nature 2003;422:198-207.

7. Vital Statistics of Japan. Statistics and Information Department, Ministers Secretariat, Ministry of Health, Labor and Welfare of Japan, 2003:25.

8. Kuramitsu Y, Nakamura K. Current progress in proteomic study of hepatitis C virus-related human hepatocellular carcinoma. Expert Rev Proteomics 2005;2:589-601.

9. Kuramitsu Y, Nakamura K. Proteomic analysis of cancer tissues: shedding light on carcinogenesis and possible biomarkers. Proteomics 2006:6:5650-5661.

10. O'Farrell PH. High-resolution two-dimensional electrophoresis of proteins. J Biol Chem 1975: 250:4007-4021.

11. Latner AL, Marshall T, Gambie M. A simplified technique of high-resolution two-dimensional electrophoresis: serum immunoglobulins. Clin ChimActa 1980;103:51-59.

12. Unlu M., Morgan ME, Minden JS. Difference gel electrophoresis: a single-gel method for detecting changes in protein extracts. Electrophoresis 1997:18:2071-2077.

13. Tonge R, Shaw J, Middleton B et al. Validation and development of fluorescence two-dimensional differential gel electrophoresis proteomics technology. Proteomics 2001:1:377-396.

14. Shaw J, Rowlinson R, Nickson J et al. Evaluation of saturation labelling two-dimensional difference gel electrophoresis fluorescent dyes. Proteomics 2003:3;1181-1195.

15. Kondo T, Seike M, Mori Y et al. Application of sensitive fluorescent dyes in linkage of laser microdissection and two-dimensional gel electrophoresis as a cancer proteomic study tool. Proteomics 2003;3:1758-1766.

16. Gygi SP, Rist B, Gerber SA et al. Quantitative analysis of complex protein mixtures using isotope-coded affinity tags. NatBiotechnol. 1999:17;994-999.

17. Wu WW, Wang G, Baek SJ et al. Comparative study of three proteomic quantitative methods, DIGE, cICAT, and iTRAQ, using 2D gel- or LC-MALDI TOF/TOF. J Proteome Res 2006;5:651-658.

18. Kuramitsu Y, Harada T, Takashima M et al. Increased expression, and phosphorylation of liver glu-tamine synthetase in well-differentiated hepatocellular carcinoma tissues of patients infected with hepatitis C virus. Electrophoresis 2006;27:1651-1658.

19. Takashima T, Kuramitsu Y, Yokoyama Y et al. Overexpression of alpha-enolase in hepatitis C virus-related hepatocellular carcinoma: association with tumor progression as determined by proteomic analysis. Proteomics 2005;5:1686-1692.

20. Yokoyama Y, Kuramitsu Y, Takashima T et al. Proteomic profiling of proteins decreased in hepatocellular carcinoma from patients infected with hepatitis C virus. Proteomics 2004:4:2111-2116.

21. Takashima T, Kuramitsu Y, Yokoyama Y et al. Proteomic profiling of heat shock protein 70 family members as biomarkers for hepatitis C virus-related hepatocellular carcinoma. Proteomics 2003:3: 2487-2493.

22. Harada T, Kuramitsu Y, Makino A et al. Expression of tropomyosin alpha-4 chain is increased in esophageal squamous cell carcinoma as evidenced by proteomic profiling by two-dimensional electrophoresis and liquid chromatography-mass spectrometry/mass spectrometry. Proteomics Clinical Applications 2007;1:215-223.

23. Mikuriya K, Kuramitsu Y, Ryozawa S et al. Expression of glycolytic enzymes is increased in pancreatic cancerous tissues as evidenced by proteomic profiling by two-dimensional electrophoresis and liquid chromatography-mass spectrometry/mass spectrometry. IntJOncol2007;30:849-855.

24. Takashima T, Kuramitsu Y, Yokoyama Y et al. Proteomic analysis of auto-antibodies in patients with hepatocellular carcinoma. Proteomics 2006;6:3894-3900.

25. Park KS, Cho SY, Kim H et al. Proteomic alterations of the variants of human aldehyde dehydrogenase isozymes correlate with hepatocellular carcinoma. Int. J. Cancer 2002;97:261-265.

26. Kim J, Kim SH, Lee SU et al. Proteome analysis of human liver tumor tissue by two-dimensional gel electrophoresis and matrix-assisted laser desorption/ionization-mass spectrometry for identification of disease-related proteins. Electrophoresis 2002;23:4142-4156.

27. Lim SO, Park SJ, Kim W et al. Proteome analysis of hepatocellular carcinoma. Biochem Biophys Res Commun 2002;291:1031-1037.

28. Li C, Hong Y, Tan YX et al. Accurate qualitative and quantitative proteomic analysis of clinical hep-atocellular carcinoma using laser capture microdissection coupled with isotope-coded affinity tag and two-dimensional liquid chromatography mass spectrometry. Mol Cell Proteomics 2004;3:399-409.

29. Fujii K, Kondo T, Yokoo H et al. Proteomic study of human hepatocellular carcinoma using two-dimensional difference gel electrophoresis with saturation cysteine dye. Proteomics 2005;5: 1411-1422.

30. Zeindl-Eberhart E, Haraida S, Liebmann S et al. Detection and identification of tumor-associated protein variants in human hepatocellular carcinomas. Hepatology 2004;39:540-549.

31. Kim W, Oe Lim S, Kim JS et al. Comparison of proteome between hepatitis B virus- and hepatitis C virus-associated hepatocellular carcinoma. Clin. Cancer Res 2003;9:5493-5500.

32. Park KS, Kim H, Kim NG et al. Proteomic analysis and molecular characterization of tissue ferritin light chain in hepatocellular carcinoma. Hepatology 2002;35:1459-1466.

33. Zhou G, Li H, DeCamp D et al. 2D differential in-gel electrophoresis for the identification of esophageal scans cell cancer-specific protein markers. Mol Cell Proteomics 2002;1:117-123.

34. Emmert-Buck MR, Gillespie JW, Paweletz CP et al. An approach to proteomic analysis of human tumors. Mol Carcinog 2000;27:158-165.

35. Zhang L, Ying W, Mao Y et al. Loss of clusterin both in serum and tissue correlates with the tumori-genesis of esophageal squamous cell carcinoma via proteomics approaches. World J Gastroenterol 2003;9:650-654.

36. Shen J, Person MD, Zhu J et al. Protein expression profiles in pancreatic adenocarcinoma compared with normal pancreatic tissue and tissue affected by pancreatitis as detected by two-dimensional gel electrophoresis and mass spectrometry. Cancer Res 2004;64:9018-9026.

37. Fujita Y, Nakanishi T, Hiramatsu M et al. Proteomics-based approach identifying auto-antibody against peroxiredoxin VI as a novel serum marker in esophageal squamous cell carcinoma. Clin Cancer Res 2006;12:6415-6420.

38. Hong S, Misek DE, Wang H et al. An autoantibody-mediated immune response to calreticulin iso-forms in pancreatic cancer. Cancer Res 2004;64:5504-5510.

39. Le Naour F, Brichory F, Misek DE et al. A distinct repertoire of autoantibodies in hepatocellular carcinoma identified by proteomic analysis. Mol CellProteomics 2002;1:197-203.

40. Hasegawa N, Mizutani K, Suzuki T et al. A comparative study of protein profiling by proteomic analysis in camptothecin-resistant PC3 and camptothecin-sensitive LNCaP human prostate cancer cells. UrolInt 2006;77:347-354.

41. Strong R, Nakanishi T, Ross D et al. Alterations in the mitochondrial proteome of adriamycin-resistant MCF-7 breast cancer cells. J Proteome Res 2006;5:2389-2395.

42. Le Moguen K, Lincet H, Deslandes E et al. Comparative proteomic analysis of cisplatin-sensitive IGROV1 ovarian carcinoma cell line and its resistant counterpart IGR0V1-R10. Proteomics 2006;6:5183-5192.

43. Smith L, Lind MJ, Welham KJ et al. Cancer proteomics and its application to discovery of therapy response markers in human cancer. Cancer 2006;107:232-241.

44. Liu Y, Liu H, Han B et al. Identification of 14-3-3sigma as a contributor to drug resistance in human breast cancer cells using functional proteomic analysis. Cancer Res 2006;66:3248-3255.

45. Mori-Iwamoto S, Kuramitsu Y, Ryozawa S et al. A proteomic profiling of gemcitabine resistance in pancreatic cancer cell lines. Molecular Medicine Reports 2008;1:429-434.

46. Mori-Iwamoto S, Kuramitsu Y, Ryozawa S et al. Proteomics finding heat shock protein 27 as a biomarker for resistance of pancreatic cancer cells to gemcitabine. International Journal of Oncology 2007;31:1345-1350.

"This page left intentionally blank."

10 Ways To Fight Off Cancer

10 Ways To Fight Off Cancer

Learning About 10 Ways Fight Off Cancer Can Have Amazing Benefits For Your Life The Best Tips On How To Keep This Killer At Bay Discovering that you or a loved one has cancer can be utterly terrifying. All the same, once you comprehend the causes of cancer and learn how to reverse those causes, you or your loved one may have more than a fighting chance of beating out cancer.

Get My Free Ebook

Post a comment