Brief Account Of The Role Of Chemistry In Cancer Chemotherapy

Chemistry has had varying roles in the discovery and development of anticancer drugs since the beginning of cancer therapies.13 In its early history, chemical modification of sulfur mustard gas led to the serendipitous discovery of the still clinically useful nitrogen mustards. Since those years, synthetic chemistry has been extensively used to modify drug leads, especially those of natural origin, and to solve the problem of the often scarce supply of natural products by developing...