In a more sophisticated approach, an HPMA conjugate known as PK-2 (FCE-28069) was designed for tumor targeting using receptor-mediated endocytosis. This copolymer contains the HPMA polymer, a Gly-Phe-Leu-Gly peptide linker, doxorubicin and also galactosamine units that are targeted at the asialoglycopro-tein receptor. Since this receptor is4?resent in hepatocytes, the prodrug is expected to be useful in hepatocarcinomas. Other ligands different to galactosamine are being explored for targeting.

10 Ways To Fight Off Cancer

10 Ways To Fight Off Cancer

Learning About 10 Ways Fight Off Cancer Can Have Amazing Benefits For Your Life The Best Tips On How To Keep This Killer At Bay Discovering that you or a loved one has cancer can be utterly terrifying. All the same, once you comprehend the causes of cancer and learn how to reverse those causes, you or your loved one may have more than a fighting chance of beating out cancer.

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