E

E7389 (ER0865), 5-6, 233 EC-16-mitomycin C conjugate, 379 EC-20, 379 Echinomycin, 207

Ecteinascidin 743 (ET-743, trabectedin),

191-182, 341, 390 Edatrexate, 36 Edotecarin, 224 Eflornithine, 422 EGFR (HER-1), 254-255

inhibitors, 258-264 EKB-569, 263 EKI-785, 263

Electroradiochemotherapy, 127 Eleutherobin, 243 Elinafide, 207 Ellipticine, 201 Elomotecan, 221

Elsamicin A, 116, 206

EMD-72000, 264

Emitefur, 26

Endostatin, 318

Enedyine(s), 122-123,125,178

Enhanced permeability and retention (EPR)

effect, 6, 369 Eniluracil (5-ethynyluracil), 28 Enzastaurin (LY-317615), 284 EO4, 186

Epicatechin gallate, 424

Epidermal growth factor, (see EGFR)

Epigallocatechin-3-gallate (EGCG), 329, 424

Epigenetic therapy of cancer, 323-337

Epirubicin (EPI), 108

Epothilones A and B, 243 D, 243

Epoxides as DNA alkylating agents, 158-159

ER-086526, 233

ErbB2, 261

Erbstatin, 259

Ergothioneine, 423

Erlotinib (OSI-774), 253, 261

Esperamicins, 122-124

Estradiol, 54, 61-66, 73-74

Estramustine, 147-148

Estramustine binding protein (EMBP), 148

Estramustine phosphate, 245

Estrogen receptor (ER), 55-56, 61-64

Estrogens involvement in carcinogenesis, 54-58

Estrone, 54

ET-743 (see ecteinascidin 743) Etanidazole, 131 Ethacrynic acid, 394, 398-401 Ethidium bromide, 339 Ethyleneimines (see aziridines) Etopophos, 216, 366-367 Etoposide, 216, 366, 390 Everolimus (RAD-001), 281 Exatecan, 221 Exemestane, 70-71

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