Fused quinoline compounds

TAS-103 is a dual topoisomerase I and II inhibitor that has marked efficacy against various lung metastatic cancers and a broad antitumor spectrum in human xeno-grafts, and it has reached clinical trials for the treatment of solid tumors.21 DNA

I Pentapeptide I

Chromophore — NH2 PO2 Intercalation

Chromophore — NH2 PO2 Intercalation

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10 Ways To Fight Off Cancer

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