Because of its high lipophilicity, it may cross the blood-brain barrier and it is effective against intracranial tumors. Another approach for designing more effective anthra-cyclines was directed to less basic compounds having a more stable glycosidic bond. One of them is anamycin,52 which after incorporation into liposomes went into clinical trials. In order to increase the topoisomerase II-mediated DNA cleavage, some groups have prepared 8- and 10-fluoroderivatives.53

10 Ways To Fight Off Cancer

10 Ways To Fight Off Cancer

Learning About 10 Ways Fight Off Cancer Can Have Amazing Benefits For Your Life The Best Tips On How To Keep This Killer At Bay Discovering that you or a loved one has cancer can be utterly terrifying. All the same, once you comprehend the causes of cancer and learn how to reverse those causes, you or your loved one may have more than a fighting chance of beating out cancer.

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