S

S-1 formulation, 41 S-16020, 203 S-3304, 315 S-9788, 394 Saframycin A, 189 Saframycin S, 189

SAHA (suberoylanilide hydroxamic acid)

(see vorinostat) Salvicine, 217, 412

SARMs (see selective androgen receptor modulators) SERMs (see selective estrogen receptor modulators) Sarcodictyins, 243 Satraplatin (JM 216), 171 SCH-221153, 319 SCH-226374, 291 SCH-58500, 298

SELDI-TOF mass spectrometry, 6 Seleciclib (see roscovitine) Selective androgen receptor modulators, 76 Selective estrogen receptor modulators, 58, 419

Semaxanib (SU-5416), 253, 266 Semustine, 161

Serine hydroxymethyl transferase

(SHMT), 19 Serine-threonine kinase inhibitors, 275-286 Sibiromycin, 196 Sickle cell anemia, 13 Sirolimus (see rapamycin) SKI-2053R, 171 SKI-606, 274 SMANCS, 122-123 SN-24771, 151, 153 SN-22995, 394 SN-23862, 360 SN-24771, 361 SN-38, 221 Soblidotin, 234 Sobuzoxane (MST-16), 218 "Soft" electrophiles, 140

Sorafenib, 253, 294 SPARC protein, 383 Spermine, 108 SPIKET-P, 235 Spongistatin 1, 235 SPPARMs (see PPAR) Squalamine, 320 Src kinase, 274

inhibitors, 274-275 Staurosporine, 223, 253, 269 Stealth liposomes, 381 Steroid hormone receptors, 54-56 Streptozotocin (streptozocin), 161 STX-64, 74

Styrene maleic acid neocarzinostatin copolymers

(see SMANCS) SU-6668, 266

Sulfatase inhibitors, 73-75 Sulforophane, 426 Sunitinib (SU-11248), 266 Superoxide dismutase (SOD), 94 Superoxide radical, 94, 127 Suramin, 270, 317 Synthadotin, 234

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