Natural Aphrodisiacs

Herbs, Oils, and Other Aphrodisiacs

This eBook guide teaches you everything that you need to know about how to use natural oils and remedies to turn your partner on in a way that you never thought was possible. Natural remedies and herbs give you access to a world of pleasure that you never know was possible, and this eBook goes through almost every type, giving you the ability to use each one of them to the most powerful effect. You will learn the best herbs and oils to choose, how to choose the right plant for you and your partner. You will also learn the tips and tricks to use herbs safely, without endangering anyone in your ever-expanding search for pleasure. All it takes is the eBook guide, and you can use the best sort of love-making supplements every created: the all-natural kind! Read more...

Herbs Oils and Other Aphrodisiacs Summary

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Simple And Complex Partial And Secondarily Generalized Tonicclonic Seizures

Assessment of toxic effects of each drug. Decreased libido and impotence were associated with both drugs (carbamazepine 13 , phenytoin 11 ). Between carbamazepine and valproic acid, carbamazepine provides superior control of complex partial seizures. Overall, data demonstrate that carbamazepine and phenytoin are preferable for treatment of partial seizures, but phenobarbital and valproic acid are also efficacious. Control of secondarily generalized tonic-clonic seizures does not differ significantly with carbamazepine, phenobarbital, or phenytoin, and val-proic acid is as effective as carbamazepine. Since secondarily generalized tonic-clonic seizures usually coexist with partial seizures, these data indicate that among drugs introduced before 1990, carbamazepine and phenytoin are the first-line drugs here.

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The plant is used in elaborate religious ceremonies, which vary from area to area. Adherents use the plant to communicate spiritually with their ancestors. In lower doses, it is used to counteract fatigue and hunger. Warriors and hunters have used it to remain awake at night. Some Europeans have claimed that it has aphrodisiac effects as well. More recently, anecdotal reports have indicated possible antiaddictive effects of iboga, stimulating a rush of scientific research into the neurochemical effects of the plant (Mash et al. 1998). Chemical Constituents

Impact of Psychoactive Drugs A Long Tradition

The human seems to have been interested in manipulating sexual urges through pharmacological means since the dawn of history. There is anecdotal mention of plants and herbs purportedly stimulating or reducing the interest in sexual activities in many ancient sources. The search for and use of aphrodisiacs have attracted much attention, but there has also been made efforts to find ways to diminish sexual desire. In the classical Chinese Empires, this was achieved by a simple procedure modifying the availability of androgens through castration. Eunuchs were favored as high state officials during many centuries. Likewise, some men of faith, like the Egyptian theologian Origen, castrated themselves in order to be relieved from sexual temptations. During the Dark Ages, castration was no longer an approved practice, but monks are said to have prepared and consumed extracts of a plant, the common rue (Ruta graveloens), supposed to inhibit sexual desire. Despite the existence of occasional...

Drugs For Androgenetic Alopecia

Finasteride (propecia) inhibits the type II isozyme of 5a-reductase, the enzyme that converts testosterone to dihydrotestosterone (see Chapter 58). The type II 5a-reductase is found in hair follicles. Balding areas of the scalp are associated with increased dihydrotesterone levels and smaller hair follicles than nonbalding areas. Orally administered finasteride (1 mg day) has been shown to variably increase hair growth in men over a 2-year period, increasing hair counts in the vertex and the frontal scalp. Finasteride is approved for use only in men. Pregnant women should not be exposed to the drug because of the potential for inducing genital abnormalities in male fetuses. Adverse effects of finasteride include decreased libido, erectile dysfunction, ejaculation disorder, and decreased ejaculate volume. Each of these occurs in < 2 of patients. Like minoxi-dil, treatment with finasteride must be continued, or any new hair growth will be lost.

Role of Pharmacotherapy

Progestin agents downregulate the estrogen receptor, a desired result in the endometrium, but potentially undesirable in the brain, heart, bone, and genitalia. Progestins generally have an overall negative effect in the central nervous system (CNS) with respect to depression and mood, and have been shown to decrease sexual desire and diminish vaginal blood flow. Available options include micronized progesterone (MP) and 19-nortestosterone Androgens play an important role in physiologic aspects of the female sexual response. However, the effect of androgen therapy on sexual function in women is controversial. Some studies have reported improvements in libido, sexual arousal, and the frequency of sexual fantasies with testosterone therapy in a variety of forms. The observation that testosterone therapy may result in improvement in mood and well-being is felt by some researchers to be most important. The central sex ster-oid's effect on mood may be what underlies sexual function in both...

Clinical Adverse Effects of Prolactin

Halbreich and Kahn 3 proposed that many of the clinical adverse consequences of HPRL could be accounted for by its effects on the HPG axis. HPRL is associated with suppression of gonadotropin pulsatile release, which in turn inhibits the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the pituitary leading to suppression of ovarian and testicular function in turn leading to hypogonadism 3, 27 . This potentially further led to a range of menstrual disorders, reduced fertility in both sexes, decreased sexual function in men and women including decreased libido, increased risk of cardiovascular disorders, galactorrhoea, anxiety and depression. Halbreich and Kahn 3 also postulated that adverse events such as an increased risk of breast cancer were possibly associated with HPRL. This hypothesis is supported by Harvey et al. 6 who identified that PRL has a direct action on breast tissue where it can act as a mitogen in the mammary gland. Furthermore, PRL...

Generalized Anxiety Disorder

Head-to-head comparisons between paroxetine and other medications in the treatment of GAD are sparse. One such study compared paroxetine 20-50 mg day with escitalopram 10-20 mg day (Bielski et al. 2005). Although there was no significant difference in efficacy between the two medications, as measured by the Ham-A, the authors noted considerably higher rates of adverse events, leading to withdrawal from the trial, in patients treated with paroxetine compared with those treated with escitalopram (22.6 vs. 6.6 ). Treatment-emergent side effects recorded more frequently with paroxetine therapy included insomnia, constipation, ejaculation disorder, anorgasmia, and decreased libido. Conversely, diarrhea and upper respiratory tract infection were more common with escitalopram than with paroxetine. One possible explanation for the divergence in dropout rates may be the seeming disparity in dose ranges between the two medications. Paroxetine was titrated to high-normal doses (between 30 and 50...

Late Distal Tubule And Collecting Duct

Blood Dyscrasias Chart

Salicylates may reduce the tubular secretion and decrease the diuretic efficacy of spironolactone, and spironolactone may alter the clearance of cardiac glycosides. Owing to its effects on other steroid receptors, spironolactone may cause gynecomastia, impotence, decreased libido, and menstrual irregularities. Spironolactone also may induce diarrhea, gastritis, gastric bleeding, and peptic ulcers (the drug is contraindicated in patients with peptic ulcers). CNS adverse effects include drowsiness, lethargy, ataxia, confusion, and headache. Spironolactone may cause rashes and, rarely, blood dyscrasias. Whether therapeutic doses of spironolactone can induce malignancies remains an open question. Strong inhibitors of CYP3A4 (see Chapter 3) may increase plasma levels of eplerenone such drugs should not be administered to patients taking eplerenone, and vice versa. Other than hyperkalemia and GI disorders, the rate of adverse events for eplerenone is similar to that of placebo.

Sex pheromone glands in the Pterygota Orthopteroidea

Unlike other cockroaches, males of Nauphoeta cinerea produce two successive chemical signals, the sex pheromone and an aphrodisiac (Menon, 1986 Sreng, 1985). Sternal glands produce the sex pheromone, seducin, that attracts the female from a distance. Tergal glands secrete the aphrodisiac, which is licked by females. As the female licks the tergal gland secretions, the male extends his abdomen and clasps her genitalia. The glandular apparatus is well developed, and is composed of five sternal glands and seven tergal glands. The glands appear as a thickening of the epithelium, without significant modification of the external cuticle. The glandular epithelium is made up of several kinds of cells ordinary epidermal cells, cells with microtubules, Class II cells (oenocytes), and especially Class III glandular units with a secretory cell and a canal cell. The sternal glands secrete primarily volatile substances and fatty acids in contrast, the tergal glands secrete primarily fatty acids and...

Common Side Effects Associated with Antipsychotic Induced Hyperprolactinaemia

Weizman et al. 52 conducted a study to look at sexual dysfunction associated with HPRL patients with renal failure undergoing haemodi-alysis. They noted that patients with high levels of PRL (130 ng ml) as compared to patients with low levels of PRL (36.3 ng ml) were clinically impotent. On treatment with bromocriptine, 4 males and 1 female showed a restoration of sexual desire and potency. These findings support the hypothesis that HPRL can be a major cause for reversible sexual dysfunction. Smith et al. 53 published one of the first controlled studies investigating the frequency and underlying mechanisms of sexual dysfunction in people on antipsychotics. Sexual dysfunction occurred in 45 of patients taking antipsychotics and 17 of non-treated controls. They concluded that HPRL was the main cause of sexual dysfunction in females (with 75 of the women being HPRL) whereas in males (with 34 of the men being HPRL) autonomic side effects were a dominant cause...

Known Effects of Drugs on Human Sexual Differentiation

It has also been reported that DES can alter sex differentiation of the human brain. Several behavioral alterations have been observed in some DES daughters 43,44 .Meyer-Bahlburg et al. 43 reported that women exposed to DES in utero were found to have less well established sex-partner relationships, and to be lower in sexual desire and enjoyment, sexual excitability, and coital functioning. In addition, Hines and Shipely 45 found that DES-exposed women showed a more masculine pattern of cerebral lateralization on a verbal task than did their sisters.

Pausinystalia johimbe K Schum Pierre ex Beille

Yohimbe bark is native to western Africa, where it was traditionally used as a sexual stimulant, primarily for men, and for the treatment of impotence. It is rich in the alkaloid yohimbine, which has been used for erectile dysfunction in medicine for more than 100 years.

Occupational Exposure to Amsonic Acid

It is surprising to learn that occupational exposures to potential EDCs at effective concentrations apparently have not been eliminated from the workplace. A series of publications from about 1990 to 1996 presented documentation of sexual impotence in chemical factory workers exposed to a DES-like stilbene derivative. The National Institute of Occupation Safety and Health conducted two studies in response to complaints of impotence and decreased libido among male workers involved in the manufacture of 4,4'-diaminostilbene-2,2' -disulfonic acid (DAS), a key ingredient in the synthesis of dyes and fluorescent whitening agents. Both current and former workers had lower serum testosterone levels 63 and reduced libido 64 as compared to control workers. In addition, duration of employment was negatively correlated with testosterone levels. These studies replicated the observations reported by Quinn et al. 65 who reported low levels of serum testosterone and problems with impotence in male...

Adverse Effects

Treating the target symptom (e.g., ondansetron for nausea, lorazepam for insomnia). More troublesome and persistent are sexual adverse effects, including anorgasmia, decreased libido, ejaculation disturbances, and erectile dysfunction. Transient adverse effects are likely the result of acute stimulation of postsynaptic serotonin receptors however, efforts to link these symptoms to specific receptor subtypes are speculative. Table 8 lists common adverse effects associated with SSRIs, and options for clinical management.

M Terazosin

Driving May affect performance of skilled tasks e.g. driving Pregnancy no evidence of teratogenicity manufacturers advise use only when potential benefit outweighs risk Breast-feeding no information available Side-effects see section 7.4.1 also reported weight gain, dsypnoea, paraesthesia, nervousness, decreased libido, thrombocytopenia, back pain, and pain in extremities Dose

Estrogen

Augmentation therapy for women during these stages of life. Perimenopause is the phase before menopause, which continues until menstruation has ceased for 12 consecutive months. Common symptoms include hot flashes, decreased libido, sleep disruption, and depression. In one study, perimenopausal women with major depression, dysthymic disorder, or minor depressive disorder received transdermal patches of 17 b -estradiol (100 mg) or placebo in a 12-week study (336). Sixty-eight percent of women treated with estradiol had remission of depression compared to 20 in the placebo group (336). An earlier study also found that estrogen was superior to placebo in reducing depressive symptoms in perimenopausal women (337). A small study of 16 perimenopausal women found that estrogen replacement therapy was effective in treating depression (338). Other studies have found that both transdermal patches and sublingual estradiol improved mood in women with premenstrual dysphoric disorder and postpartum...

Methyldopa

ADVERSE EFFECTS AND PRECAUTIONS In addition to lowering blood pressure, the active metabolite of methyldopa acts on a2 adrenergic receptors in the brainstem to inhibit the centers that are responsible for wakefulness and alertness, producing sedation that is largely transient. Decreased mental acuity and lassitude may persist in some patients, and depression occurs occasionally. Medullary centers that control salivation are inhibited by a adrenergic receptors, and methyldopa may produce dry mouth. Other side effects related to pharmacological effects in the CNS include decreased libido, parkinsonian signs, and hyperprolactinemia that may become sufficiently pronounced to cause galactorrhea. In individuals who have sinoatrial node dysfunction, methyldopa may precipitate severe bradycardia and sinus arrest, including that which occurs with carotid sinus hypersensitivity.

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