Bpcs Of Neomycin

In fine powderb form for preparation of Soluble Aspirin Tablets and Soluble Aspirin, Phenacetin and Codeine Tablets

Surface area of not less than 7000 cm2 g01 determined by air permeability method

Ultrafine powder to be used for preparation of solid dosage forms to achieve a satisfactory rate of solution Colloidal water-miscible type differentiated from nondispersible form by size

Fine powder to be used for preparation of solid dosage forms

Prepared from dithranol in fine powder form Most of the individual particles have a diameter not greater than 5 ßm; no individual particle has a length greater than 20 ßm

95% of particles have a maximum diameter of not more than 5 ßm

Particle size determined from disintegrated tablet generally up to 5 ßm in maximum dimension although larger particles may occasionally be greater than 30 ßm All subject to limit on particle size of Hydrocortisone or Hydrocortisone Acetate. See Hydrocortisone Acetate Ointment BP, Hydrocortisone Cream BPC, Hydrocortisone and Neomycin Cream BPC, Hydrocortisone and Neomycin Ear Drops and Eye Drops BPC, Hydrocortisone Eye Ointment BPC, Hydrocortisone Lotion BPC and Hydrocortisone Suppositories BPC See Insulin Zinc Suspension (Crystalline) BP, Insulin Zinc Suspension (Amorphous) BP, Biphasic Insulin Injection BP As for Ergotamine Aerosol Inhalation BPC No particle of nystatin has a maximum diameter greater than 75 ßm

As for Ergotamine Aerosol Inhalation BPC Microcrystalline phenolphthaleinc to be used in Liquid Paraffin Emulsion with Phenolphthalein BPC to prevent sedimentation of the phenolphthalein As for Ergotamine Aerosol Inhalation BPC

a Modified from E. G. Salole, in Practical Pharmaceutical Chemistry (ed. A. H. Beckett and J. B. Stenlake), vol. 2, Athlone Press, London, 1987. bThe following terms, inter alia, are used in the description of powders in the British Pharmacopoeia and the Pharmaceutical Codex 1994: Coarse powder: a powder all the particles of which pass through a sieve with a nominal mesh aperture of 1700 ^m and not more than 40% by weight pass through a sieve with a nominal aperture of 355 ^m.

Moderately coarse powder: a powder all the particles of which pass through a sieve with a nominal mesh aperture of 710 ^m and not more than 40% by weight pass through a sieve with a nominal aperture of 250 ^m.

Moderately fine powder: a powder all the particles of which pass through a sieve with a nominal mesh aperture of 355 ^m and not more than 40% by weight pass through a sieve with a nominal aperture of 180 ^m.

Fine powder: a powder all the particles of which pass through a sieve with a nominal mesh aperture of 180 ^m and not more than 40% by weight pass through a sieve with a nominal aperture of 125 ^m.

Very fine powder: a powder all the particles of which pass through a sieve with a nominal mesh aperture of 125 ^m and not more than 40% by weight pass through a sieve with a nominal aperture of 45 ^m.

Microfine powder: a powder of which not less than 90% by weight of the particles pass through a sieve with a nominal mesh diameter of 45 ^m. Superfine powder: a powder of which not less than 90% by number of the particles are less than 10 ^m in size.

Ultrafine powder: a powder of which the maximum diameter of 90% of the particles is not greater than 5 ^m and of which the diameter of none is greater than 50 ^m. c BPC 1973, p. 679.

BP, British Pharmacopoeia; EP, European Pharmacopoeia; PC, Pharmaceutical Codex, 12th edn, 1994; BPC, British Pharmacopoeial Codex.

Table 1.8 Influence of formulation on the potency ratios of pentobarbital in the form of the sodium salt and the free

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