Ch3

Structure VII Dipivoyl epinephrine (dipivefrine; compare with Structure VI)

iris after applications of prednisolone in solution. When the drug was incorporated into the lens, aqueous and corneal levels of the drug were two- to threefold higher 4 hours after insertion.

The Alza Ocusert device (Fig. 9.39) releases controlled amounts of pilocarpine over a period of 7 days and is designed for the treatment of glaucoma. It comprises a drug reservoir in which pilocarpine is embedded in an alginic acid matrix, and this is bounded by

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