Cn Cn

CN CN CN CN CN CN

CN CN CN CN CN CN

Q Attached drug ^ ^ Encapsulated drug

O Solubilizing group -C&- Targeting moiety

Figure 8.4 (a) A two dimensional view of a dendrimer with 64 cyano functional groups. It is possible to trap small to medium-size molecules in dendrimers which have pores of appropriate dimensions between the branches of the structure. (Reproduced from H. W. Gibson, Nature, 371, 106, (1994).) (b) A diagrammatic representation of possible sites for cova-lent attachment of drugs, solubilising groups and targeting moieties, and encapsulation of drugs.

Q Attached drug ^ ^ Encapsulated drug

O Solubilizing group -C&- Targeting moiety

Figure 8.4 (a) A two dimensional view of a dendrimer with 64 cyano functional groups. It is possible to trap small to medium-size molecules in dendrimers which have pores of appropriate dimensions between the branches of the structure. (Reproduced from H. W. Gibson, Nature, 371, 106, (1994).) (b) A diagrammatic representation of possible sites for cova-lent attachment of drugs, solubilising groups and targeting moieties, and encapsulation of drugs.

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