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Figure 5.3 Solubility of (a) indometacin, (b) chlorpromazine and (c) oxytetracycline as a function of pH, plotted as logarithm of the solubility.

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Figure 5.3 Solubility of (a) indometacin, (b) chlorpromazine and (c) oxytetracycline as a function of pH, plotted as logarithm of the solubility.

mimicking the intestinal fluid highlighted some limitations of this equation and the authors cautioned against its uncritical use.8

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