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a Reproduced from S. P. Eriksen, Am. J. Pharm. Educ, 28, 47 (1964).

Table 1.4 Intrinsic dissolution rates of the crystal

forms of oxyphenbutazonea

Sample

Intrinsic dissolution rateb

(jjg min01 cm~2)

Solvate C

21.05 ± 0.02

Solvate B

18.54 ± 0.47

Anhydrate

14.91 ± 0.47

Hemihydrate

17.01 ± 0.78

Monohydrate

9.13 ± 0.23

a Reproduced from A. P. Lotter and J. G. van der Walt, J. Pharm. Sci.,

77, 1047 (1988).

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