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Rotating disc (d)

Shaker

Figure 12.1 Six configurations of simple dissolution test apparatus: (a) the Wruble method in which the dose form is rotated in a container of solvent; (b) a simple beaker method; (c) an apparatus in which the dosage form is in a cradle which oscillates vertically; (d) the rotating disc method to determine the intrinsic dissolution characteristics of a compressed powder; (e) method in which the dosage form is placed in a medium which is shaken and (f) a method in which the decreasing size of suspensions is measured on dissolution.

Rotating disc (d)

Shaker

Coulter Counter method

Figure 12.1 Six configurations of simple dissolution test apparatus: (a) the Wruble method in which the dose form is rotated in a container of solvent; (b) a simple beaker method; (c) an apparatus in which the dosage form is in a cradle which oscillates vertically; (d) the rotating disc method to determine the intrinsic dissolution characteristics of a compressed powder; (e) method in which the dosage form is placed in a medium which is shaken and (f) a method in which the decreasing size of suspensions is measured on dissolution.

Centring (or tilt]

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