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b This would be the osmolality of the drug if the activity coefficient were equal to 1 in the

full-strength preparation. The osmolalities of serial dilutions of the

drug were plotted against the concentrations of the solution, and a least-squares regression line was drawn. The value for the

osmolality of the full-strength

solution was then estimated from the line. This is

the 'calculated available milliosmoles'.

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