Osmotic properties of drug solutions

A nonvolatile solute added to a solvent affects not only the magnitude of the vapour pressure above the solvent but also the freezing point and the boiling point to an extent that is proportional to the relative number of solute molecules present, rather than to the weight concentration of the solute. Properties that are dependent on the number of molecules in solution in this way are referred to as colligative properties, and the most important of such properties from a pharmaceutical viewpoint is the osmotic pressure.

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