The chemical decomposition of drugs

In this section we examine various ways in which drugs in both liquid and solid formulations can lose their activity, so that we can be aware of those chemical groups which, when present in drug molecules, can cause stability problems. We will later see how to prevent or minimise the chemical breakdown for each type of decomposition process. Although each decomposition scheme is considered separately, it should be noted that with some drug molecules more than one type of decomposition may be occurring at the same time; this, of course, complicates the analysis of the system.

Structure Chemical class

II H II Imide

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