Geneticallyengineered cells

Many groups have carried out extensive research on artificial cells containing genetically-engineered cells. This more recent and very important area will be discussed in detail in a later chapter, including potential applications in amyotrophic lateral sclerosis, dwarfism, pain treatment, IgG1 plasmacytosis, hemophilia B, Parkinsonism and axotomized septal cholinergic neurons, tumor suppression and other areas (Basic etal., 1996; Tan etal., 1996; Al-Hendy etal., 1996; Okada et al., 1997; Dalle et al., 1999; Saitoh etal., 1995; Hagihara et al., 1997; Winn etal., 1994; Aebischer et al., 1996; Bloch et al., 2004; Bachoud-Levi et al., 2000; Xu et al., 2002; Cirone et al., 2002). To avoid the need for implantation, we studied the oral use of artificial cells containing genetically-engineered nonpathogenic E. coli DH5 cells to lower systemic urea in renal failure rats (Prakash and Chang, 1996; Chang, 1997).

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