Pharmacologic Management of Myofascial Pain and Dysfunction

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Source: Oral and Maxillofacial Surgery Clinics of North America. 7(1): 87-97. February 1995.

Summary: This article on the pharmacologic management of myofascial pain and dysfunction is from an issue of Oral and Maxillofacial Clinics on the medical management of temporomandibular disorders (TMD). The authors discuss the most frequently used classes of drugs, providing information about their mechanism of action, indications and contraindications, methods of use, and possible adverse side effects. Specific drugs discussed include anti-inflammatory medications, including nonsteroidal anti-inflammatory drugs, and corticosteroids; muscle relaxants (other than benzodiazepines); antianxiety medications; antidepressant medication; opiate narcotic analgesics; and local anesthetics. A final section covers the placebo effect. The author emphasizes the importance of understanding the patient in terms of compliance and tolerance of side effects in order to achieve successful management with pharmacologic therapy. 2 figures. 6 tables. 25 references. (AA-M).

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