Active Transport

Any process whereby a substance is transported from a region of low concentration to a region of higher concentration by coupling the otherwise unfavorable AGdiffusion with the highly favorable AGhydrolysis for ATP conversion to ADP and orthophosphate. Other metabolites displaying high group transfer potential can replace ATP in the hydrolase-type reaction, as long as sufficient free energy is liberated. Contrary to generally held ideas that active transport requires a membrane, one can also have active transport in a single compartment, such as the cytoplasm. The only condition that must be fulfilled is that the transport occurs against a concentration gradient. See Membrane Transporters; Ion Pumps; AGdiffusion

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