System Description

The system is a single loop system, with branch loops for each floor of the building supplying WFI at 80°C. Users take water at 80°C direct from the loop with single lines or through coolers at 20°C via single lines. The basic materials of construction are standard pipe hand welded stainless steel 1.4571 (equivalent to 316 Ti), vessels and coolers (also 316 Ti), sterile type filters, stainless steel ball valves, and 316 Ti stainless steel control valves. In recent months, the demand for WFI has grown, and the system is now stretched beyond its capacity. The system is frequently drained, which causes a system shut-down, in turn the pumps fail and the loop cools.

The system can be divided into three sections: pre-treatment, generation and storage & distribution.

1. Pre-Treatment - City water is filtered through a rough filter in order to remove particles, and then treated in mixed-bed deionisers. The water is then further treated via sterile filters.

2. Generation - the pre-treated water is fed into distillation columns, the resulting distillate is fed into a dedicated storage tank.

1. Storage and Distribution - There are two storage tanks for the WFI

system, both of which are heated. The main loop is divided into three sub-loops, each serving different areas of the facility. The WFI is circulated around the loop at 80°C via a centrifugal pump. The return water from all three sub-loops is routed via a heat exchanger prior to being re-circulated, and does not circulated via the storage tanks. A schematic of the system is shown in Figure 35.

Multiple effect distillation column

Multiple effect distillation column

Figure 35, Schematic Diagram of Existing WFI System - Case Study No. 2

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