Acetylcholinesterase Inhibitors

Acetylcholinesterase (AChE) terminates the action of acetylcholine (ACh) at the junctions of the various cholinergic nerve endings with their effector organs or postsynaptic sites. Inhibitors of AChE, or anticholinesterase (anti-ChE) agents, cause ACh to accumulate in the vicinity of cholinergic nerve terminals and thus can produce effects equivalent to excessive stimulation of cholinergic receptors throughout the central and peripheral nervous systems; such is the basis of their clinical use and their adverse effects. Since cholinergic neurotransmission is widely distributed across animal species, anti-ChE agents are also effective toxins (e.g., agricultural insecticides, pesticides, and, regrettably, chemical warfare "nerve gases").

Diabetes 2

Diabetes 2

Diabetes is a disease that affects the way your body uses food. Normally, your body converts sugars, starches and other foods into a form of sugar called glucose. Your body uses glucose for fuel. The cells receive the glucose through the bloodstream. They then use insulin a hormone made by the pancreas to absorb the glucose, convert it into energy, and either use it or store it for later use. Learn more...

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