Adverse Effects Precautions

The untoward effects of NE resemble those of Epi, although there typically is greater elevation of blood pressure with NE. Excessive doses cause severe hypertension. Care must be taken that necrosis and sloughing do not occur at the site of intravenous injection owing to extravasation of the drug. The infusion should be made high in the limb, preferably through a long plastic cannula extending centrally. Impaired circulation at injection sites, with or without extravasation of NE, may be relieved by infiltrating the area with phentolamine, an a receptor antagonist. Blood pressure must be determined frequently. Reduced blood flow to organs such as kidney and intestines is a constant danger with the use of NE.

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Blood Pressure Health

Blood Pressure Health

Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...

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