Adverse Effects

Blood pressure and heart rate may increase significantly during dobutamine administration, requiring reduction of infusion rate; hypertensive patients may exhibit such an exaggerated pres-sor response more frequently. Since dobutamine facilitates AV conduction, patients with atrial fibrillation are at risk of marked increases in ventricular response rates; digoxin or other measures may be required to prevent this from occurring. Some patients may develop ventricular ectopic activity. As with any inotropic agent, dobutamine may increase the size of an infarct by increasing myocardial O2 demand. The efficacy of dobutamine for more than a few days is uncertain; there is evidence of the development of tolerance.

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Blood Pressure Health

Blood Pressure Health

Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...

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