Liposomal amphotericin B (ambisome) cures nearly 100% of cases of visceral leishmaniasis and has become the drug of choice for antimonial-resistant disease. Likely due to pharmacokinetic considerations, it is not useful against cutaneous or mucosal leishmaniasis. The recommended dose for the treatment of visceral leishmaniasis is 3 mg/kg/day intravenously for days 1—5, 14, and 21, with the dose being increased to 4 mg/kg and extended to days 1—5, 10, 17, 24, 31, and 38 for immunosuppressed patients. Shorter courses of the drug provide a lower-cost alternative. Cure rates are ~90% with either regimen.

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Blood Pressure Health

Blood Pressure Health

Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...

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