Cardiovascular System

The classical response of blood vessels to 5-HT is contraction, particularly in the splanchnic, renal, pulmonary, and cerebral vasculatures. This response also occurs in bronchial smooth muscle. 5-HT induces a variety of cardiac responses that result from activation of multiple 5-HT receptor subtypes, stimulation or inhibition of autonomic nerve activity, and reflex responses to 5-HT. Thus, 5-HT has positive inotropic and chronotropic actions on the heart that may be blunted

by simultaneous stimulation of afferent

nerves from baroreceptors and chemoreceptors. An effect

Table 11-2

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Blood Pressure Health

Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...

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