Comparison of Uncoated and Enteric-Coated Pancreatic Enzyme Preparations*

Uncoated Preparations Enteric-Coated Preparations

Number of tablets or capsules 2-8 2-3

required per dose

Acid suppression required Yes No

Site of delivery Duodenum More distal small bowel and beyond

Symptoms relieved Pain; malabsorption Malabsorption

*The major components of these preparations are a lipase and a protease (see Table 37-10).

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