Chloroprocaine (nesacaine), an ester local anesthetic, is a chlorinated derivative of procaine with rapid onset, short duration of action, and reduced acute toxicity due to rapid metabolism (plasma t1/2 ~25 seconds). A higher-than-expected incidence of muscular back pain following epidural anesthesia with 2-chloroprocaine has been reported; this back pain is thought to be due to tetany in the paraspinus muscles, which may be a consequence of Ca2+ binding by the EDTA included as a preservative; the incidence of back pain appears to be related to the volume of drug injected and its use for skin infiltration.

Dealing With Back Pain

Dealing With Back Pain

Deal With Your Pain, Lead A Wonderful Life An Live Like A 'Normal' Person. Before I really start telling you anything about me or finding out anything about you, I want you to know that I sympathize with you. Not only is it one of the most painful experiences to have backpain. Not only is it the number one excuse for employees not coming into work. But perhaps just as significantly, it is something that I suffered from for years.

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