Copper deficiency is extremely rare, and there is no evidence that copper ever need be added to a normal diet. Even in clinical states associated with hypocupremia (sprue, celiac disease, and nephrotic syndrome), effects of copper deficiency usually are not demonstrable. Anemia due to copper deficiency has been described in individuals who have undergone intestinal bypass surgery, in those who are receiving parenteral nutrition, in malnourished infants, and in patients ingesting excessive amounts of zinc. While an inherited disorder affecting copper transport (Menkes' disease) is associated with reduced activity of several copper-dependent enzymes, this disease is not associated with hematological abnormalities.

The outstanding findings in copper deficiency are leukopenia, particularly granulocytopenia, and anemia; the anemia is not always microcytic. When a low plasma copper concentration is determined in the presence of leukopenia and anemia, a therapeutic trial with copper is appropriate. Daily doses up to 0.1 mg/kg of cupric sulfate have been given by mouth, or 1-2 mg/day may be added to the solution of nutrients for parenteral administration.

Was this article helpful?

0 0
Why Gluten Free

Why Gluten Free

What Is The Gluten Free Diet And What You Need To Know Before You Try It. You may have heard the term gluten free, and you may even have a general idea as to what it means to eat a gluten free diet. Most people believe this type of diet is a curse for those who simply cannot tolerate the protein known as gluten, as they will never be able to eat any food that contains wheat, rye, barley, malts, or triticale.

Get My Free Ebook

Post a comment