DA (3,4-dihydroxyphenylethylamine; Table 10-1) is the metabolic precursor of NE and Epi; it is a central neurotransmitter particularly important in the regulation of movement (see Chapters 12, 18, and 20). In the periphery, DA is synthesized in epithelial cells of the proximal tubule and is thought to exert local diuretic and natriuretic effects. DA is a substrate for both MAO and COMT and thus is ineffective when administered orally. Classification of DA receptors is described in Chapters 12 and 20.

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Diabetes 2

Diabetes 2

Diabetes is a disease that affects the way your body uses food. Normally, your body converts sugars, starches and other foods into a form of sugar called glucose. Your body uses glucose for fuel. The cells receive the glucose through the bloodstream. They then use insulin a hormone made by the pancreas to absorb the glucose, convert it into energy, and either use it or store it for later use. Learn more...

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