DA (3,4-dihydroxyphenylethylamine; Table 10-1) is the metabolic precursor of NE and Epi; it is a central neurotransmitter particularly important in the regulation of movement (see Chapters 12, 18, and 20). In the periphery, DA is synthesized in epithelial cells of the proximal tubule and is thought to exert local diuretic and natriuretic effects. DA is a substrate for both MAO and COMT and thus is ineffective when administered orally. Classification of DA receptors is described in Chapters 12 and 20.

Blood Pressure Health

Blood Pressure Health

Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...

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