Ephedrine is an agonist at both a and b receptors and also enhances release of NE from sympathetic neurons; thus, it is a mixed-acting sympathomimetic. Ephedrine does not contain a catechol moiety and is effective after oral administration. The drug stimulates heart rate and cardiac output and variably increases peripheral resistance; as a result, it usually increases blood pressure. Activation of b receptors in the lungs promotes bronchodilation. Ephedrine is a potent CNS stimulant. After oral administration, effects of the drug may persist for several hours. Ephedrine is eliminated in the urine largely as unchanged drug, with a t122 of ~3-6 hours. A steroisomer of ephedrine, pseudoephedrine, is used as a nasal mucosal vasoconstrictor and decongestant (see below)

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Blood Pressure Health

Blood Pressure Health

Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...

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