Gr138676

CCK8 » gastrin

5 = CCK4 CCK8 > gastrin 5 = CCK4 [Pro34] NPY NPY • NPY

GPCR: G /n coupled

GPCR: Gs coupled

GPCR: G^ coupled? Autoreceptor function:

inhibits transmitter release GPCR: G , G. coupled? GPCR: Gq/n coupled; modulatory; regulates ion channels, second messenger production, and protein phosphorylation GPCR: G coupled GPCR: Gq/n coupled

GPCR: Gq/n coupled; modulatory; regulates ion channels, second messenger production, and protein phosphorylation

GPCR: G^n and Gs coupled GPCR: Gq/n coupled GPCR: G^ coupled

Mepyramine

Ranitidine, famotidine, Cimetidine H.,: Thioperamide

JNJ777120 V1A: SR49059

Orn^OTj 8, atosiban SR140333 LY303870 CP99994 GR94800 GR159897 SR142802 SR223412 [Pro7]NKB

Devazepide; lorglumide CI988; L365260; YM022

GPCR: G /n coupled SR48692

(Continued)

Overview of Transmitter Pharmacology in the Central Nervous System (Continued)

Transmitter

Transporter Blocker*

Receptor

Agonists

Receptor-Effector Coupling

Selective Antagonists

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