Somatodendritic Autoreceptors (5-HT1A)

Presynaptic Autoreceptors (5-HT1D)

FIGURE 11-2 Two classes of 5-HT autoreceptors with differential localizations. Somatodendritic 5-HT1A autoreceptors decrease raphe cell firing when activated by 5-HT released from axon collaterals of the same or adjacent neurons. The receptor subtype of the presynaptic autoreceptor on axon terminals in the human forebrain has different pharmacological properties and has been classified as 5-HT1D; this receptor modulates the release of 5-HT. Postsynaptic 5-HT1 receptors are also indicated.

5-HT1D Receptor

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Blood Pressure Health

Blood Pressure Health

Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...

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