Alkylating Agents

In 1942, Goodman, Gilman, and colleagues launched the modern era of cancer chemotherapy with clinical studies of several nitrogen mustards in patients with lymphoma. At present five major types of alkylating agents are used in the chemotherapy of neoplastic diseases: (1) the nitrogen mustards, (2) the ethyleneimines, (3) the alkyl sulfonates, (4) the nitrosoureas, and (5) the triazenes. The methylhydrazine and platinum complexes also are included here, even though they do not formally alkylate DNA and use a different means to form covalent adducts with DNA.

Diabetes 2

Diabetes 2

Diabetes is a disease that affects the way your body uses food. Normally, your body converts sugars, starches and other foods into a form of sugar called glucose. Your body uses glucose for fuel. The cells receive the glucose through the bloodstream. They then use insulin a hormone made by the pancreas to absorb the glucose, convert it into energy, and either use it or store it for later use. Learn more...

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