Info

+++

Dynorphin B

+

+

+++

a-Neoendorphin

+

+

+++

Activities of drugs are given at the receptors for which the agent has reasonable affinity. +, agonist; antagonist. The number of symbols (+, —) is an indication of potency; the ratio for a given drug denotes selectivity. These values were obtained primarily from animal studies and should be extrapolated to human beings with caution. Both b-funaltrexamine and naloxonazine are irreversible m antagonists, but b-funaltrexamine also has reversible k agonist activity. P, partial agonist; DAMGO, CTOP, DPDPE, DSLET, see Table 21-1.

Activities of drugs are given at the receptors for which the agent has reasonable affinity. +, agonist; antagonist. The number of symbols (+, —) is an indication of potency; the ratio for a given drug denotes selectivity. These values were obtained primarily from animal studies and should be extrapolated to human beings with caution. Both b-funaltrexamine and naloxonazine are irreversible m antagonists, but b-funaltrexamine also has reversible k agonist activity. P, partial agonist; DAMGO, CTOP, DPDPE, DSLET, see Table 21-1.

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