Info

Guinea pig ileum

m

Decrease contraction

No effect

Mouse vas deferens

s

Decrease contraction

No effect

The actions listed for antagonists are seen with the antagonist alone. All the correlations in this table are based on studies in rats and mice, which occasionally show species differences. Thus, any extensions of these associations to humans are tentative. Clinical studies do indicate that m receptors elicit analgesia spinally and supraspinally. Preliminary work with a synthetic opioid peptide, [d-Ala2,d-Leu5]enkephalin, suggests that intrathecal d agonists are analgesic in humans.

The actions listed for antagonists are seen with the antagonist alone. All the correlations in this table are based on studies in rats and mice, which occasionally show species differences. Thus, any extensions of these associations to humans are tentative. Clinical studies do indicate that m receptors elicit analgesia spinally and supraspinally. Preliminary work with a synthetic opioid peptide, [d-Ala2,d-Leu5]enkephalin, suggests that intrathecal d agonists are analgesic in humans.

Opioid Receptor Signaling and Consequent Intracellular Events

Diabetes 2

Diabetes 2

Diabetes is a disease that affects the way your body uses food. Normally, your body converts sugars, starches and other foods into a form of sugar called glucose. Your body uses glucose for fuel. The cells receive the glucose through the bloodstream. They then use insulin a hormone made by the pancreas to absorb the glucose, convert it into energy, and either use it or store it for later use. Learn more...

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