Some Actions of 5-HT in the Gastrointestinal Tract




Enterochromaffin cells

Enteric ganglion cells (presynaptic)

Enteric ganglion cells (postsynaptic)

Smooth muscle, intestinal Smooth muscle, stomach fundus Smooth muscle, esophagus

Release of 5-HT Inhibition of 5-HT release Release of ACh Inhibition of ACh release Fast depolarization Slow depolarization Contraction Contraction Contraction

5-HT3 5-HT4 5-HT4

5-HTip, 5-htib




5-HT2B 5-HT4

ABBREVIATION: ACh, acetylcholine

ABBREVIATION: ACh, acetylcholine

Vascular Injury

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Diabetes 2

Diabetes 2

Diabetes is a disease that affects the way your body uses food. Normally, your body converts sugars, starches and other foods into a form of sugar called glucose. Your body uses glucose for fuel. The cells receive the glucose through the bloodstream. They then use insulin a hormone made by the pancreas to absorb the glucose, convert it into energy, and either use it or store it for later use. Learn more...

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