Mdr2

Mouse

PPARa

Ciprofibrate (0.05% w/w in diet)

Effect of Ligand

T Transcription activity (promoter assay) T Expression in duodenum in healthy subjects ■!• Oral bioavailability of digoxin in healthy subjects

■!• AUC of talinolol after IV and oral administration in healthy subjects

T Expression in duodenum in healthy subjects

T Expression in human hepatocytes T Expression in HepG2 cells T Expression in mouse hepatocyte

T Expression in hepatocyte of PXR KO mice (promoter assay) T Expression in rat hepatocytes T Transcription activity (promoter assay) T Transcription activity (promoter assay) ■!• RAR mediated transcription Indirect effect on HNF1a expression T Expression in hepatoma cells T Expression in the liver

Families in the Human Solute Carrier Superfamily

Number Selected

Gene

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Blood Pressure Health

Blood Pressure Health

Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...

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