Mephentermine (wyamine sulfate) acts both directly and indirectly. After an intramuscular injection, the onset of action is prompt (within 5-15 minutes), and effects may last for several hours. Since the drug releases NE, cardiac contraction is enhanced, and cardiac output and systolic and diastolic pressures usually are increased. The change in heart rate is variable, depending on the degree of vagal tone. Adverse effects are related to CNS stimulation, excessive rises in blood pressure, and arrhythmias. Mephentermine is used to prevent hypotension, which frequently accompanies spinal anesthesia.

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Blood Pressure Health

Blood Pressure Health

Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...

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