Pilocarpine is used in the treatment of glaucoma, where it is instilled into the eye usually as a 0.5-4% solution. An ocular insert (ocusert pilo-20) that releases 20 |Xg of pilocarpine per hour over 7 days also is marketed for the control of elevated intraocular pressure. Pilocarpine usually is better tolerated than are the anticholinesterases and is the standard cholinergic agent for the treatment of open-angle glaucoma. Reduction of intraocular pressure occurs within a few minutes and lasts 4-8 hours. The ophthalmic use of pilocarpine alone and in combination with other agents is discussed in Chapter 63. The miotic action of pilocarpine is useful in reversing a narrow-angle glaucoma attack and overcoming the mydriasis produced by atropine; alternated with mydriatics, pilocarpine is employed to break adhesions between the iris and the lens.

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Diabetes 2

Diabetes 2

Diabetes is a disease that affects the way your body uses food. Normally, your body converts sugars, starches and other foods into a form of sugar called glucose. Your body uses glucose for fuel. The cells receive the glucose through the bloodstream. They then use insulin a hormone made by the pancreas to absorb the glucose, convert it into energy, and either use it or store it for later use. Learn more...

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