Catecholamines increase the output of glucose from the liver, predominantly via b receptors, although a receptors may contribute, and thus, a receptor antagonists may reduce glucose release. a2A Receptors facilitate platelet aggregation; the effect of blockade of platelet a2 receptors in vivo is not clear. Activation of a2 receptors in the pancreatic islets suppresses insulin secretion; conversely, their blockade may facilitate insulin release (see Chapter 60). Alpha receptor antagonists reduce smooth muscle tone in the prostate and neck of the bladder, thereby decreasing resistance to urine outflow in benign prostatic hypertrophy (see below).
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All you need is a proper diet of fresh fruits and vegetables and get plenty of exercise and you'll be fine. Ever heard those words from your doctor? If that's all heshe recommends then you're missing out an important ingredient for health that he's not telling you. Fact is that you can adhere to the strictest diet, watch everything you eat and get the exercise of amarathon runner and still come down with diabetic complications. Diet, exercise and standard drug treatments simply aren't enough to help keep your diabetes under control.