Paralytic Ileus And Atony Of The Urinary Bladder

In the treatment of both these conditions, neostigmine generally is preferred among the anti-ChE agents. The direct parasympathomimetic agents (Chapter 7) are employed for the same purposes. The usual subcutaneous dose of neostigmine methylsulfate for postoperative paralytic ileus is 0.5 mg, given as needed. Peristaltic activity commences 10—30 minutes after parenteral administration, whereas 2—4 hours are required after oral administration of neostigmine bromide (15—30 mg). It may be necessary to assist evacuation with a small low enema or gas with a rectal tube.

A similar dose of neostigmine is used for the treatment of atony of the detrusor muscle of the urinary bladder.

Neostigmine should not be used when the intestine or urinary bladder is obstructed, when peritonitis is present, when the viability of the bowel is doubtful, or when bowel dysfunction results from inflammatory bowel disease.

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  • sven
    Why neostigmine is preferred in paralytic ileus or atony?
    3 years ago
    Which drug id used in the treatment of paralytic ileus and atony of the bladder?
    1 year ago

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