Pentamidine

Pentamidine is a positively charged aromatic diamidine:

l-UN

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0CH2(CH2)3CH20 PENTAMIDINE

Pentamidine isethionate is marketed for injection (pentam 300) or for use as an aerosol (nebu-pent). One milligram of pentamidine base is equivalent to 1.74 mg of the pentamidine isethion-ate. The isethionate salt is highly water soluble. Solutions should be used promptly because pentamidine is unstable in solution.

ANTIPROTOZOAL EFFECTS The diamidines are effective for the treatment of T. brucei gambiense sleeping sickness but not T. brucei rhodesiense or T. cruzi infections. They also are useful for treating antimony-resistant leishmania.

Diabetes 2

Diabetes 2

Diabetes is a disease that affects the way your body uses food. Normally, your body converts sugars, starches and other foods into a form of sugar called glucose. Your body uses glucose for fuel. The cells receive the glucose through the bloodstream. They then use insulin a hormone made by the pancreas to absorb the glucose, convert it into energy, and either use it or store it for later use. Learn more...

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