Piperazine

Piperazine

A number of substituted piperazine derivatives have anthelmintic activity, but none apart from diethylcarbamazine has found a place in human therapeutics.

Piperazine is highly effective against A. lumbricoides and E. vermicularis. The predominant effect of piperazine on Ascaris is a temporary paralysis that results in expulsion of the worm by peristalsis. Piperazine acts as a GABA-receptor agonist. By increasing Cl~ conductance of the Ascaris muscle membrane, the drug produces hyperpolarization that leads to flaccid paralysis.

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Diabetes 2

Diabetes 2

Diabetes is a disease that affects the way your body uses food. Normally, your body converts sugars, starches and other foods into a form of sugar called glucose. Your body uses glucose for fuel. The cells receive the glucose through the bloodstream. They then use insulin a hormone made by the pancreas to absorb the glucose, convert it into energy, and either use it or store it for later use. Learn more...

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