Piperazine

Piperazine

A number of substituted piperazine derivatives have anthelmintic activity, but none apart from diethylcarbamazine has found a place in human therapeutics.

Piperazine is highly effective against A. lumbricoides and E. vermicularis. The predominant effect of piperazine on Ascaris is a temporary paralysis that results in expulsion of the worm by peristalsis. Piperazine acts as a GABA-receptor agonist. By increasing Cl~ conductance of the Ascaris muscle membrane, the drug produces hyperpolarization that leads to flaccid paralysis.

Blood Pressure Health

Blood Pressure Health

Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...

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