R

^Alphabetical footnotes refer to alterations of the general formula; symbolic footnotes are used for other comments. ^Not available for clinical use in the U.S. ^Major metabolite of chlordiazepoxide.

§Major metabolite of diazepam and others; also referred to as nordiazepam and desmethyldiazepam.

aNo substituent at position 4, except for chlordiazepoxide and demoxepam, which are N-oxides; R4 is —CH3 in flumazenil, in which there is no double bond between positions 4 and 5; R4 is=O in clobazam, in which position 4 is C and position 5 is N.

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