The Science Of Drug Therapy

Optimal therapeutic decisions are based on an evaluation of the patient and assessment of the evidence for efficacy and safety of treatment. Therapy must be guided by an understanding of drug pharmacokinetics and pharmacodynamics that is integrated with patient-focused information. Well-designed and executed clinical trials provide the scientific evidence that informs most therapeutic decisions; they may be supplemented by observational studies, particularly in assessing adverse effects that elude detection in clinical trials.

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