Epilepsy Phenytoin is effective against partial and tonic-clonic but not absence seizures. Phenytoin preparations differ significantly in bioavailability and rate of absorption. In general, patients should consistently be treated with the same drug from a single manufacturer. However, if it becomes necessary to temporarily switch between products, care should be taken to select a therapeutically equivalent product and patients should be monitored for loss of seizure control or onset of new toxicities.
Some cases of trigeminal and related neuralgias appear to respond to phenytoin, but carba-mazepine is preferred.
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