Therapeutic Uses

Ketorolac (toradol, ultram) has been used as a short-term alternative (<5 days) to opioids for the treatment of moderate-to-severe pain and is administered intramuscularly, intravenously, or orally. Unlike the case with opioids, tolerance, withdrawal, and respiratory depression do not occur. Like other NSAIDs, aspirin sensitivity is a contraindication to the use of ketorolac. Typical doses are 30-60 mg (intramuscular); 15-30 mg (intravenous); and 5-30 mg (oral). Ketorolac is used widely in postoperative patients, but it should not be used for routine obstetric analgesia. Topical (ophthalmic) ketorolac is FDA-approved for the treatment of seasonal allergic conjunctivitis and postoperative ocular inflammation after cataract extraction.

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